Is hyaluronic acid injection safe?

About 10 years ago when we began preparing the clinic in Japan, we inofrmed on the safety of subcutaneous infusions such as hyaluronic acid in the US at a lecture meeting for doctors, but at that time I have mentioned the serious complications of blindness and skin necrosis many times.
In the United States some of these complications had already been announced.
Although hyaluronic acid itself is generally a safe dermal filler, it is rarely happened that there are events in which facial blood vessels become clogged due to treatment to the vicinity of the eyebrows and nose.
Although highly skilled technique is required for such injections, hyaluronic acid still has some medicines to dissolve it, but in many cases it can be reduced somehow, because there are no such drugs for permanent type of infusions , It will be a serious consequence when a problem occurs.
In our hospital, we do not use it as injectable material except for hyaluronic acid made from USA or France or autologous fat.

Dr. Kure